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Melanotan 2 TANEXIN

Melanotan-2 10mg vial

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Melanotan 2

DRS Labs


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Rating: 4 out of 70 reviews

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Tanexin - Melanotan 2

Melanotan 2 profile:

The synthetic cyclic heptapeptide, Melanotan II (also known as Tanex or MT-II, developed at the University of Arizona) an analogue of alpha-melanotropin, is a receptor agonist of the Melanocortin peptide hormone, α-melanocyte-stimulating hormone (α-MSH), that stimulates the body to make melanin. Melanocortin peptides are neuropeptides derived from the precursor molecule pro-opiomelanocortin (POMC) by tissue-specific splicing; they include adrenocorticotropic hormone (ACTH) and a-melanocyte-stimulating hormone (a-MSH).1

Clinical trials have shown that MT-II safely promotes melanogenesis and aphrodisiac effects. As a result is has a potential to be developed into a tanning and libido increasing preparation. There have also been many studies on MT-II and its effectiveness as: being neurotrophic and neuroprotective; being able to increase insulin sensitivity, improve glucose tolerance as well as decrease food intake and lower body weight.1

Melanin, the dark pigment of a tan, is known to protect the body from skin damage caused by exposure to ultra-violet (UV) radiation. MT-II induces a protective tan without the need to expose the skin to harmful levels of UV radiation. Using potentiometric titration and ultraviolet (UV) spectrophotometry, MT-II has been previously evaluated for the prevention of sunlight induced cancers without the use of chemotherapy.1

Studies, alternating MT-II with Saline (placebo), for 2 consecutive weeks yielded interesting results. Mild nausea, not requiring antiemetic treatment, was reported at most MT-II dose levels as well as the onset of spontaneous, penile erections which were intermittently experienced for l-5 hours after MT-II dosing, depending on the MT-II dose. After 1 week of dosing, patients had increased pigmentation in the face and upper body. Such results demonstrate that MT-II has tanning activity with only 5 low doses every other day by subcutaneous injection.1

Alpha-melanocyte stimulating hormone (α-MSH) is a linear, tridecapeptide which is synthesized and secreted by the pars intermedia of lower vertebrate pituitary glands. α-MSH lacks corticotropic activity and instead, is used to control integumental coloration by binding to melanocortin (MC) receptors on the plasma membranes of melanocytes in the skin.2

MT-II chronically reduces body weight, without the need of long term calorific restriction.3 Obesity is characterized by increased body fat stores resulting from an imbalance between energy intake and energy expenditure. Increased adiposity causes insulin resistance. Type 2 diabetes mellitus (DM) develops when the increased demand for insulin is not compensated due to impaired pancreatic beta cells. Fat accumulation is the primary cause of insulin resistance, although studies show that the central nervous system also plays a critical role.4

The central melanocortin system is a critical regulator of energy homeostasis. Pharmacological and genetic studies have revealed pivotal roles for the central melanocortin pathway in the regulation of satiety and energy expenditure. The melanocortin receptors 3 and 4 (MC3/4 receptors) are required for optimal function of the central melanocortin system.3 These receptors regulate appetite along with numerous metabolic pathways, including thermogenesis, and lipolysis. The α-melanocyte-stimulating hormone (α-MSH) is the endogenous agonist ligand for the MC3/4 receptors. The more stable synthetic melanocortinergic peptide is the MT-II, a non-selective agonist of MC receptors.

There is evidence supporting MTII as a long-term modulator of energy balance, e.g. it can suppress appetite therefore, it may help combat obesity.3 MT-II also increases insulin sensitivity, improves glucose tolerance4, as well as being neurotrophic and neuroprotective.5

Effects of peripheral administration of MT-II, on insulin sensitivity and glucose tolerance were previously examined.4 Subcutaneous administration of MT-II had decreased food intake and body weight in OLETF rats. MT-II group showed more sensitivity to insulin compared with that allowed to eat at libitum or pair-fed group in insulin tolerance tests on day 9.4

MT-II can significantly enhance the recovery of sensory function following a crush lesion of the sciatic nerve.5 In addition, it has been also observed to possesses neuroprotective properties, as it partially protects the nerve from a toxic neuropathy induced by cisplatin.5

Several of the melanocortins, including α-MSH, have been shown to improve recovery of function after peripheral nerve damage, as well as after experimental spinal cord injury.


0.8 kDa peptide containing 7 amino acid residues.



Melanotan 2, Melanotan II, MT-2, MT-II, Melanotide, Tanexin.

Physical Appearance:

Sterile Filtered White lyophilized (freeze-dried) powder.


MT-2 has an affinity to melanocortin receptors MC3R and MC4R.


>99.8% (HPLC analyzed).


Add 1 ml of sterile diluent and let the lyophilized pellet dissolve completely.


Store lyophilized protein at -20 °C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 °C for a limited period of time. The lyophilized protein remains stable until the expiry date when stored at -20 °C.


Chemical synthesis


Product is prepared for LABORATORY RESEARCH USE ONLY. The product may not be used for other purposes.


  1. Lan EL, et al. Preformulation studies with melanotan-II: a potential skin cancer chemopreventive peptide. J Pharm Sci. 1994 Aug;83(8):1081-4.
  2. Dorr RT, et al. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sci. 1996;58(20):1777-84.
  3. Côté I, et al. Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction. Can J Physiol Pharmacol. 2017 Feb;95(2):206-214. doi: 10.1139/cjpp-2016-0290.
  4. Banno R, et al. The melanocortin agonist melanotan II increases insulin sensitivity in OLETF rats. Peptides. 2004 Aug;25(8):1279-86.
  5. Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83.

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Melanotan 2 - Gives Brilliant tan!

I find this product amazing. I first heard of it while living in Phoenix Arizona a long time ago. Then my sister and her boyfriend used it and went really brown. I have only used 1 and a half vials and have a beautiful dark tan. The first vial I dont think I used properly as I jabbed myself before going to bed every night. At the end I hardly notices any change in my skin colour. Then I staarted reading other peoples stories in INternet and found out I should have been taking it just before sunbathing as it lasts only 1 hour in your body. SO I do that every time I go sunbathing and straight away I noticed that it helps me not to burn. Still use sunlotion, but usually I burn and now I dont. Also I feel it accentuates the tan about 10 times more than if you dont use it. My legs never usually go brown and now they are. Also the funny thing is that if I stuff my face with all I shouldnt at a weekend I have not shot up a couple of kilos LOL It helps keep weight balance. I dont know whether or not it has anything to do with it or not, but my neuralgia I have had for a long time is gone... I definatly recomend this but remember less is more. If you give yourself too higher dose you will only feel sick and it wont do anything good for you - the body only absorbs a certain amount so dont throw it aweay. You are supposed to add 1ml of bac water - I have added 1.5ml and it has given me a brilliant tan ;-)


Great service

I ordered Melanotan and got very good service via FB messenger, everything arranged to my advantage and a very fast shipment.



I have ordered this product for years and I have had no issues with this company. However, I ordered 4 weeks ago and I have still not received my items due to it been out of stock, which should have been advertised on the website before letting customers buy. I ordered my item and I had to send a email asking why it was taking so long, to then be alerted of this issue that it was out of stock. I have waited 1 month for my products and I have had to email constantly to get any update on my order. I have requested a refund and sent my details over. I'm still yet to receive a refund. I am very disappointed in the service I have received as I have ordered from this company for 3 years and I have been a loyal customer. Poor communication all round. I have not been left with a bill and no item.
SELLER RESPONSE: Sorry for the inconvenience caused. We are looking into your order and will sort it out for you. Also, we are changing the management, therefore, this should not happen again.


rich tan!

Low dosage to start off (don't want to feel jittery!)
won't find a better product on the market that gives you a deep rich tan.
Will definetely be spreading the word!!



Fast delivery, great communication and an excellent product. Have been buying for years and will continue to do so


Melanotan 2

I dont use this product that often, only once a year for my main holiday.

But with trying a few different companies this product is definitely the best out there.

I am fair skinned & do not tan on sunbeds or in the sun, this product gives me a really dark tan & i always keep my colour for at least a few months after the holiday, even although i do not use anymore than 1 vial.

Take small doses to start for first few days incase of nausea but i 100% recommend buying this product & also buying from this company.


Great service & product

Product works. Delivery took a bit of time but the important thing is that the product is 100%. Tan is coming nicely. Two thumbs up !


Superb Service

Item is the best on the Market. Quick delivery and superb comms. Thankyou Drlabs



super i do twice a week and its mind blowing better tan, sex drive and better than viagra or ciales, use 6 hours bevore intimacie and she wil be supriced! ;)



Had trouble to start with and posted last review on wrong product. Although it took some time sort due to supply issues. DRS have delivered. Still waiting on other products on back order which I hope to receive soon. Thanks

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