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RAD140

RAD-140 10mg 50tabs

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RAD-140

£56.50

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RAD140
Rating: 5 out of 6 reviews

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  • Reviews (6)

Radirol SARM (Selective Androgen Receptor Modulator). Investigational name: RAD-140

Radirol profile:

Radirol (RAD-140 or RAD 140) is a potent, orally bioavailable and nonsteroidal selective androgen receptor modulator (SARM).1

RAD140 is efficacy and potency selective.1 It exhibits a fully anabolic effect on muscle with reduced efficacy on the prostate and seminal vesicles.2 RAD140 can also stimulate muscle weight increase at lower dose than that required to stimulate prostate weight increase in vivo.1 RAD140 can moderately antagonise seminal vesicle stimulation induced by testosterone.2 RAD140 has excellent pharmacokinetics and has been shown to be a potent anabolic in nonhuman primates.1

Although RAD 140 can induce dramatic increase in body weight over a short time it does not promote elevation of liver enzyme transaminase levels even at a dose 10-fold greater than the fully effective dose. Clinical chemistry had also showed RAD 140 lipid (LDL, HDL and triglycerides) lowering effects.1,2

RAD-140 (2-chloro-4-{[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino}-3-methylbenzonitrile) (also known as RAD-140, RAD140) is an investigational selective androgen receptor modulator (SARM) under development by Radius Health, Inc. for potential therapeutic benefit of conditions such as muscle wasting and breast cancer.2 It has a very good preclinical profile, having completed preclinical toxicology in both rats and monkeys. RAD140 has been also prepared for phase I clinical studies as a potential treatment of severe weight loss due to cancer cachexia.1

Description:

Formula: C20H16ClN5O2
Mol. Weight: 393.82634 g/mol

Molecular Structure:

 RAD140

Synonyms:

Radirol, RAD-140, RAD140, SARM, Selective Androgen Receptor Modulator.

Physical Appearance

White tablets.

Specificity:

Radirol is capable to selectively interact with androgen receptors in certain tissues.

Purity:

>99.8% (HPLC analysed).

Stability:

Store at 20 °C in dry place until the expiration date.

Source:

Chemical Synthesis

Usage:

Product is prepared for LABORATORY RESEARCH USE ONLY. The product may not be used for other purposes.

References:

  1. Miller, Chris P. et al. “Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140.” ACS Medicinal Chemistry Letters 2.2 (2011): 124–129. PMC.
  2. Jayaraman, Anusha et al. “Selective Androgen Receptor Modulator RAD140 Is Neuroprotective in Cultured Neurons and Kainate-Lesioned Male Rats.” Endocrinology 155.4 (2014): 1398–1406. PMC.

 

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Evelina T.

06/15/2017
5
Superb Product

Great product. Recommended.
I am currently carrying out comparative analysis of SARM effects in canine cancer cachexia and so far - results are really promising! Although more data are required, RAD-140 intake has yielded significant weight increase over short term (2-5weeks), compared to that of a control group. Of course there is a lot more work to be done but I simply wanted to spread the word and also express my gratitude to DRS Labs for the great service and such a high quality product.
I have been a customer for a long time now and have not been disappointed yet.
Shipping is fast and effective. Although sometimes there is a bit of a waiting time - it is understandable, these products are in high demand and it is very difficult to find a reputable supplier. So I personally don't mind waiting since I am 100% sure the product will be delivered to me. Good prices and products are always of the highest quality.
Thank you DRS, and looking forward to doing more business with you. 5*

 
geraint

06/6/2017
5
AMAZING RESULTS!!!

These bad boys are incredible for cutting even on just 10mg per day. As always amazing super fast service.

 
David

04/20/2017
5
Great results

Great product Great muscle fullness on 20mg day

 
Armando

02/20/2017
5
Best place to buy RAD

Extremely satisfied. Had best ever experience shopping online with DRS Labs. Natalie answered all my questions, I had concerns with security as well as temperature concerns due to the delivery, all was addressed immediately and had product very next day! you cant ask for more.
Product itself very well packed and works amazing. Definitely buying it soon again

 
Russell

02/16/2017
5
Excellent product and shopping experience

Great product, results better than expected. Easy checkout and fast delivery. I will purchase it again.

 
adam

09/30/2016
5
Highly Recommended

Great product from a reputable supplier. Fast shipping and high quality. Have been testing this as part of my physiology paper for a few weeks now, and results are astonishing.

 
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