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LGD-4033 SARMs Ligandrol View full size

LGD-4033 SARMs Ligandrol

LGD-4033 2mg x 50tabs

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£60.65

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LGD-4033 SARMs Ligandrol
Rating: 5 out of 7 reviews

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  • Reviews (7)

LGD-4033 SARMs (Selective Androgen Receptor Modulator). Investigational names: (Ligandrol ) LGD-4033

LGD-4033 profile:

Potential negative effect of testosterone on prostate has led to the development of selective androgen receptor modulators that activate tissue-selective androgenic signalling, SARMs (Selective Androgen Receptor Modulators), a class of compounds used to treat muscle wasting associated with cancer, acute and chronic illness, and age-related muscle loss.

Ligandrol (LGD-4033) is a non-steroidal oral SARM which binds AR with high affinity (Ki of ~1 nM) and selectivity. It elicits therapeutic effect of testosterone with an improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action, and an oral route of administration.

In animal models this SARM demonstrates a robust selectivity for bone and muscle versus prostate and sebaceous glands, as well as anabolic and anti-resorptive activities in muscles and bones. Phase I clinical trial study showed Ligandrol to be safe, with a favourable pharacokinetic profile: the safety and tolerability have been established up to doses of 22mg; levels of haemoglobin, alanine aminotransferase, prostate-specific antigen, aspartate aminotransferase, and QT intervals are not altered significantly at any dose; the lean body mass is increased even during a short period without changes in prostate-specific antigen; it has a long elimination half-life as well as dose-proportional accumulation upon multiple dosing.

 LGD-4033 administration can be associated with a dose-dependent suppression of total testosterone, SHBG (sex hormone-binding globulin), HDL (high density lipoprotein), cholesterol, and triglyceride levels.

Description:

Formula: 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile
Formula: C15H14F6N2
Molecular weight: 336.28
Molecular Structure:

Synonyms:

Ligandrol, SARMs, Selective Androgen Receptor Modulator, LGD-4033.

Physical Appearance:

White tablets.

Specificity:

LGD-4033 selectively binds androgen receptors in certain tissues.

Purity:

>99.9% (HPLC analyzed).

Stability:

Store at at 20 °C in dry place until the expiration date.

Source: Chemical Synthesis

Usage:

Product is prepared for LABORATORY RESEARCH USE ONLY. The product may not be used for other purposes.

  • Buy LGD-4033 (Ligandrol) SARMs UK Online - Fast Shipping
Grant

05/7/2017
5
Lgd4033

Great compound works excellent, great site to buy from, the test rat is 4weeks in and weighing in 15lbs more AND IT SHOWS. fantastic product.

 
Paul

03/7/2017
5
The best sarm!

everything hassle free, from ordering to shipping, a fantastic sarm used for my research

 
Addison

03/3/2017
5
sarms

wish i found this supplier ages ago. very satisfied with product and service they provide

 
George

03/2/2017
5
Excellent SARM

Excellent service, Delivered fast ordered on tuesday, was delivered today. very satisfied!

 
Thomas

10/27/2015
5

Excellent service. Product is in line with my expectations

 
Boriss

06/22/2015
5
LGD

nice to buy from this shop any of products, because it's always ship in time with pure product, which is always working well, I'll say perfect product for beginners test subjects, only be careful with the doses, some of them have some negative sides, some negative said effect from Ostarine.

 
gabriel

12/2/2014
5

perfect product and super fast shipping.
excellent seller 5 stars

 
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